8 January 2026 By beuty_space 0

These Are The Most Revolutionary Skincare Products According To Dermatologists


One of the many reasons I am utterly obsessed with beauty is the constant innovation in the category. In my capacity as a beauty journalist for British Vogue, there is not a day that goes by that I don’t read about a new “revolutionary” skincare product that piques my interest – be it an ingredient, delivery system or advancement.

The most revolutionary skincare – according to the experts – at a glance:

In this article:

2025 has been a transformative year for anti-ageing, with ingredients like peptides and exosomes rivalling retinoids in their hype. Consultant dermatologist Dr Ophelia Veraitch explains, “Retinoids have been the cornerstone of evidence-based skincare for decades. There are new EU restrictions on retinol concentrations, forcing a shift as over-the-counter brands will be forced to find alternative, proven anti-ageing actives. Peptides and exosomes are constantly discussed, yet we still don’t have a universal definition or clear standards for what they should be or how they should behave in a topical. Still, in the long term, these biological signalling ingredients are likely to form the backbone of the most effective topical treatments.”

She believes 2026 will be “the most dynamic and fast-moving years this industry has ever seen” and spotlights the following: “DNA-repair enzymes and probiotic-based formulations look genuinely interesting, offering new ways to address inflammation, barrier repair, and photoaging. Topical polynucleotides are another emerging category; very few exist on the market yet, but several are in development and could be transformative if the clinical data holds. Injectable polynucleotides (’salmon sperm’) have provided surprising, good results in-clinic, so the development of topical polynucleotides is quite exciting for me.”

However, this constant evolution can often leave me asking the question of whether it is worth disrupting my current skincare routine to incorporate said new product launch – and whether to encourage Vogue readers to do the same. Will it be as revolutionary as it seems? Well, that was my thought process for the collation of this very article.

I reached out to dermatologists, surgeons and aesthetic doctors at the top of their fields – ones who have studied for decades, who are hands-on with patients of all skin types and conditions on a daily basis. I want to find out the exact skincare heroes they believe truly deserve “revolutionary skincare” status. Here is what they told me.


Meet the experts

  • Dr Ophelia Veraitch is a consultant dermatologist specialising in hair loss, acne and eczema, rosacea and hyperpigmentation
  • Dr Wassim Taktouk is one of the most sought-after aesthetic doctors in London
  • Dr Eirini Merika is a consultant dermatologist specialising in adult and paediatric dermatology
  • Dr Sophia Opel is a consultant plastic and reconstructive surgeon specialising in skin cancer excision and reconstruction, hand surgery, scar management and trauma reconstruction
  • Dr Anita Jatan is a consultant plastic and reconstructive surgeon, specialising in hand surgery
  • Dr Sach Mohan is the founder of Revere Clinics and specialises in fillers and injectables
  • Dr Priya Verma is a cosmetic doctor, specialising in laser skin tightening
  • Dr Hao Hanson is a cosmetic doctor at The Cosmetic Skin Clinic and specialises in non-surgical aesthetic treatments

The most revolutionary skincare – according to the experts

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Consultant dermatologist Dr Ophelia Veraitch raves about the technology that Cantabria Labs’ Heliocare includes in its bestselling SPF collection, but particularly in its daily supplement. She explains, “Heliocare offers enhanced protection from within, reducing sun damage with powerful antioxidants like Fernblock. They also help reduce Polymorphic Light Eruption (PLE), a red, blotchy skin reaction caused by sun exposure.”

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Skinceuticals

C E Ferulic Vitamin C Serum

“C E Ferulic by SkinCeuticals remains the gold standard in vitamin C serums,” says Dr Wassim Taktouk, aesthetic doctor. “Its formulation – a synergistic blend of vitamin C, vitamin E and ferulic acid – enhances the potency of vitamin C by up to eight times compared with using vitamin C alone.” Moreover, it’s the science-backed nature of the time-tested formula that the expert believes gives it revolutionary status. He explains, “Even two decades after its launch, C E Ferulic continues to be rigorously studied as skincare science evolves. Beyond protecting against early signs of environmental damage, we’re now seeing its relevance in addressing emerging modern stressors such as pollution and atmospheric metals.”

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Eucerin

Hyaluron-Filler Epigenetics Serum

For consultant dermatologist Dr Eirini Merika, who is impressed at the innovation in the skincare space, it is a challenge to choose just one product she deems revolutionary. “In an era of ample cosmeceutical serums and creams containing functional compounds such as antioxidants, hyaluronic acid, botanicals, peptides and growth factors promising skin rejuvenation and repair, it is hard to pick a winner.” However, she says, “The challenge remains: can we reverse skin ageing? Can it really be done? Well, we are certainly closer!” For this, the expert spotlights Eucerin’s Hyaluron-Filler Epigenetics Serum, which contains epicelline. “This is meant to help reverse or reset such age-related epigenetic changes in skin cells, helping them regain a ‘younger’ gene expression profile.”

She breaks down the science: “Epigenetic changes are chemical modifications to DNA or the proteins that package DNA that affect how genes are turned on or off without changing the DNA sequence itself. Age-related epigenetic changes in skin cells accumulate over time and under external stressors such as sun, pollution, stress and lifestyle. Correcting those epigenetic changes can potentially lead to reactivation of youth-associated genes, that is, genes whose activity contributes to youthful skin traits like elasticity, firmness and healthy renewal.”

The dermatologist concludes that “The concept of youth gene reactivation through a topical skin product is revolutionary and offers a completely different approach to skin ageing, fighting it right at its source. It is likely to bring on a new era in skincare.” Watch this space.

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“As a plastic surgeon, I spend much of my time talking to patients about scars – how they form, how they mature, and how we can help them heal as beautifully as possible,” reconstructive Surgeon Dr Sophia Opel reveals. “One of the most effective tools I recommend is medical-grade silicone. Its brilliance lies in its simplicity: silicone creates a soft, breathable barrier over a healing scar, regulating hydration and gently reducing excess collagen. This controlled environment allows scars to flatten, soften and fade more evenly, offering improved cosmetic outcomes with minimal effort, discomfort or risk.”

She continues, “Silicone works across all skin types, ages and scar causes and its non-invasive nature makes it an ideal first-line treatment. Accessible, affordable and backed by clinical evidence, silicone consistently makes a visible difference to my patients and restores confidence. Medical-grade silicone comes in several trusted forms, including gels such as Kelo-Cote and Dermatix, and silicone sheets like Cica-Care. Gels are typically applied twice daily to clean, dry skin, while sheets are worn for 12–24 hours a day to achieve the most refined results.”

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Neova Cu3 Tissue Repair Recovery Cream With Copper Peptide Complex

“It’s miraculous,” Dr Sach Mohan says of the copper peptide-infused formula of Neova’s Cu3 skin rejuvenating cream. “After laser resurfacing or post-peels, it heals the tissue. I’m a scientist, and I do split face so I can see the results.” He finds that when using this product, the recovery rate is accelerated. The brand says it can also be used on burns, on post-waxing irritation, on diaper rash and on dry, chapped skin.

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Lab31 Micropeptide Needle Power Serum

“One of the most revolutionary skincare formulations of recent years is the Lab31 Micropeptide Needle Power Serum,” believes cosmetic doctor, Dr Priya Verma. “It combines advanced micro-peptide technology with needle-inspired delivery mechanics to create microscopic channels in the skin, enhancing penetration of active ingredients while stimulating cellular rejuvenation. The result is visibly smoother, firmer and more resilient skin, making it a truly standout innovation in next-generation home skincare.”

Noble Panacea

The Absolute Active Replenishing Moisturiser

Dr Hanson, cosmetic doctor at The Cosmetic Skin Clinic, is a fan of the rich, protective, hydrating and radiance-boosting Noble Panacea moisturiser. He says, “A pinnacle of molecular precision, this cream uses Nobel Prize-winning OSMV technology to deliver actives with extraordinary control and potency. It does not just hydrate. It orchestrates a calibrated rejuvenation process at the cellular level.”

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OneSkin OS01 Topical Supplement

This daily moisturiser is also in the bathroom cabinet of Dr Hanson. He tells us, “Powered by the OS01 peptide, this formula helps reduce ageing cells that contribute to inflammation and a decline in skin quality. It is one of the first topical products created to support healthier, younger-looking skin at a deeper level.”